Abacavir, Lamivudine and Zidovudine - Systemic
Brand Names
Trizivir
Abacavir, Lamivudine and Zidovudine *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
In deciding to using a medication, the
chance of taking the drug must be weighed against the good it will do.
This is a decision you will make. For abacavir, lamivudine,
and zidovudine combination the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual
or allergy to abacavir, lamivudine, or zidovudine
This drug must not be taken if you have an allergy
to it or to abacavir, because it could cause another severe reaction that
may result in death.
Also tell your health care professional if you
are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy care
Abacavir, lamivudine and zidovudine combination
has not been studied in pregnant women. However, abacavir has been found
to cause birth defects and other problems in pets at doses many times the
human dose and zidovudine has been studied in pets and causes birth defects
when given in very high doses. Before taking this abacavir, lamivudine and
zidovudine combination, make sure your family doctor knows if you are pregnant or
if you may become pregnant.
Breast-feeding problem
Zidovudine passes into human breast milk. It
is not known whether abacavir or lamivudine passes into human breast milk.
However, if your baby does not already have the AIDS virus, there is a risk
that you could pass it to your baby by breast-feeding. Talk to your family doctor
first if you are thinking about breast-feeding your baby.
Use for Children
Abacavir, lamivudine and zidovudine combination
contains a fixed amount of each drug that can't be decreased. Therefore,
this drug is not recommended for diseaseds who weigh less than 40 kilograms
- 88 pounds because the amounts of abacavir, lamivudine and zidovudine in
this product can't be adjusted for smaller body sizes.
Adolescents Abacavir, lamivudine and zidovudine combination
contains a fixed amount of each drug that can't be decreased. Therefore,
this drug is not recommended for diseaseds who weigh less than 40 kilograms
- 88 pounds because the amounts of abacavir, lamivudine and zidovudine in
this product can't be adjusted for smaller body sizes.
Elderly care
Many medication have not been studied specifically
in elderly people. Therefore, it may not be known whether they work exactly
the same way they do in adults people or if they cause various side effects
or problems in elderly people. There is no special info comparing use
of abacavir, lamivudine and zidovudine combination in the elderly with use
in other age groups.
Drug interactions
Although certain medication must not be using together at all, in other cases
two various medication may be using together even if an interaction might
occur. In these cases, your family doctor may want to change the dose, or other precautions
may be necessary. When you are taking abacavir, lamivudine and zidovudine
combination, it is especially important that your health care professional
know if you are taking any of the following:
-
Amphotericin B by injection - Fungizone
-
Antineoplastics - cancer drug
-
Azathioprine - Imuran
-
Chloramphenicol - Chloromycetin
-
Clozapine - Clozaril
-
Colchicine
-
Didanosine - Videx
-
Eflornithine - Ornidyl
-
Flucytosine - Ancobon
-
Ganciclovir - Cytovene
-
Interferon - Intron A, Roferon-A Using any of these medication
with the combination drug may cause blood problems to become worse
-
Abacavir - Ziagen
-
Lamivudine - Epivir
-
Zidovudine - Retrovir Using additional abacavir, lamivudine,
or zidovudine with the combination drug may increase the risk of side
effects of abacavir, lamivudine, or zidovudine
-
Doxorubicin - Adriamycin
-
Ribavirin - Virazole
-
Stavudine - Zerit Use of these medication with abacavir,
lamivudine and zidovudine combination may result in these medication or the
combination not working as well as they must
Other Information for using
The presence of other medical problems may effect the use of abacavir,
lamivudine and zidovudine combination. Make sure you tell your family doctor if
you have any other medical problems, especially:
-
Blood problems, including anemia and decreased bone marrow production Abacavir,
lamivudine and zidovudine combination may make these conditions worse
-
Kidney disease
-
Liver disease Patients with kidney or liver disease may have
more side effects
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